Facile Total Synthesis of (+)-Spinoxazine B
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چکیده
منابع مشابه
A Facile Total Synthesis of Imatinib Base and Its Analogues
Imatinib and its analogues were successfully synthesized by an improved method in 19.5– 46.2% total yield of six main steps. Pyrimidinyl amine was prepared by the reaction of enaminone and guanidine nitrate without the use of a toxic cyanamide. N-(2Methyl-5-nitrophenyl)-4-(pyridin-3-yl) pyrimidin-2-amine as a key intermediate for the synthesis of imatinib was prepared by coppercatalyzed N-aryla...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2018
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.c18-00693